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Patent 6376657 on Hoodia

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The patent # 6376657 for the hoodia as an appetite suppressant was assigned to CSIR from South Africa.

The inventors are Van Heerden; Fanie Retief (Fairland, ZA), Vleggaar; Robert (Pretoria, ZA), Horak; Roelof Marthinus (Pretoria, ZA), Learmonth; Robin Alec (Pretoria, ZA), Maharaj; Vinesh (Pretoria, ZA), Whittal; Rory Desmond (Pretoria, ZA).

The abstract literally mentions "A pharmaceutical composition which contains an extract obtainable from a plant of the genus Trichocaulon or Hoodia containing an appetite suppressant agent having the formula (1). A process for obtaining the extract and a process for synthesizing compound (1) and its analogues and derivatives is also provided. The invention also extends to the use of such extracts and compound (1) and its analogues for the manufacture of medicaments having appetite suppressant activity. The invention further provides novel intermediates for the synthesis of compound (1)."

You may read the complete Hoodia patent description including the basic research and clinical trials here.

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